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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOPEY2
All Species:
20.91
Human Site:
T2224
Identified Species:
35.38
UniProt:
Q9Y3R5
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3R5
NP_005119.2
2298
258184
T2224
I
S
S
S
D
E
I
T
M
K
S
E
F
P
L
Chimpanzee
Pan troglodytes
XP_531552
2298
258112
T2224
I
S
S
S
D
E
I
T
M
K
S
E
F
P
L
Rhesus Macaque
Macaca mulatta
XP_001084653
2286
256620
T2212
I
S
S
S
D
E
I
T
M
K
T
E
F
P
L
Dog
Lupus familis
XP_544874
2297
257913
T2223
V
G
S
S
D
E
I
T
M
K
N
E
F
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHQ6
2295
257491
T2221
I
G
S
S
D
E
I
T
R
K
K
E
F
P
L
Rat
Rattus norvegicus
XP_001055500
2294
257490
T2220
I
S
S
S
E
E
I
T
R
K
K
E
F
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512569
2247
251024
M2173
S
N
S
V
N
Q
R
M
V
K
C
E
F
P
L
Chicken
Gallus gallus
XP_001232723
2283
257889
I2206
R
N
N
T
D
E
G
I
S
K
R
H
K
F
P
Frog
Xenopus laevis
Q642P2
2270
256829
W2195
K
T
T
E
D
P
K
W
K
R
T
E
F
P
L
Zebra Danio
Brachydanio rerio
NP_956904
817
86774
G744
V
F
T
S
Q
L
A
G
P
S
S
K
S
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBE8
2599
291169
D2518
R
R
V
A
R
L
M
D
M
K
Y
T
S
Q
S
Honey Bee
Apis mellifera
XP_395999
2434
273219
A2361
V
P
H
I
T
R
I
A
K
L
M
D
S
K
Y
Nematode Worm
Caenorhab. elegans
Q9XW10
2417
267134
K2316
V
S
S
V
S
A
D
K
T
E
I
F
K
P
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03921
1698
194669
E1625
A
L
V
D
E
I
A
E
F
K
D
Y
E
I
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.8
89.9
N.A.
86.4
86.4
N.A.
73.9
75.2
69
21.9
N.A.
27.6
32.1
22.3
N.A.
Protein Similarity:
100
99.7
96
94.6
N.A.
92.4
92.5
N.A.
83
85.4
82
28.7
N.A.
47
53.2
40.9
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
80
80
N.A.
40
20
33.3
13.3
N.A.
13.3
6.6
20
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
80
86.6
N.A.
66.6
40
60
33.3
N.A.
26.6
20
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
15
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
8
50
0
8
8
0
0
8
8
0
0
0
% D
% Glu:
0
0
0
8
15
50
0
8
0
8
0
58
8
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
8
0
0
8
58
8
8
% F
% Gly:
0
15
0
0
0
0
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
36
0
0
8
0
8
50
8
0
0
8
0
0
15
0
% I
% Lys:
8
0
0
0
0
0
8
8
15
72
15
8
15
8
0
% K
% Leu:
0
8
0
0
0
15
0
0
0
8
0
0
0
0
58
% L
% Met:
0
0
0
0
0
0
8
8
36
0
8
0
0
0
0
% M
% Asn:
0
15
8
0
8
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
8
0
0
0
8
0
0
8
0
0
0
0
65
8
% P
% Gln:
0
0
0
0
8
8
0
0
0
0
0
0
0
8
0
% Q
% Arg:
15
8
0
0
8
8
8
0
15
8
8
0
0
0
0
% R
% Ser:
8
36
58
50
8
0
0
0
8
8
22
0
22
0
8
% S
% Thr:
0
8
15
8
8
0
0
43
8
0
15
8
0
0
15
% T
% Val:
29
0
15
15
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _